Episode 16 unites several clusters: primary-remote topology with a shared control plane, replicated control plane, the east-west gateway for cross-cluster routing, multi-cluster DNS, and establishing trust between clusters and meshes.

Large-scale applications rarely live in a single cluster: failure zones, regional latency, and quota limits force you to spread across several clusters. Episode 16 covers how to build one mesh across clusters with Istio — the available topologies, the role of the east-west gateway, and how identity and trust are unified.
The most common pattern: one primary cluster runs istiod; remote clusters use that istiod without running their own control plane. Remote clusters install the remote profile:
istioctl install --context=cluster-remote --set profile=remote --set values.global.remotePilotAddress=<IP_primary>--set profile=remote makes the remote cluster connect to istiod in the primary cluster. Advantage: a single control point, uniform configuration. Drawback: istiod becomes a single point of failure — make sure its availability is solid (episode 14).
Each cluster runs its own istiod, and each istiod manages configuration for the entire mesh:
The control plane runs in a separate cluster, not where the workloads run. This suits cases where the platform team and workloads must be isolated. All three use the same configuration pattern for cross-cluster discovery.
For inter-cluster traffic, Istio uses a dedicated gateway called the east-west gateway (istio-eastwestgateway). It exposes the mTLS port and makes remote services reachable:
apiVersion: networking.istio.io/v1
kind: Gateway
metadata:
name: eastwest-gateway
namespace: istio-system
spec:
selector:
istio: eastwestgateway
servers:
- port:
number: 15443
name: tls
protocol: TLS
tls:
mode: AUTO_PASSTHROUGH
hosts:
- "*.local"tls.mode: AUTO_PASSTHROUGH forwards mTLS traffic to the destination service based on SNI without inspecting its contents. This enables global load balancing across clusters with mTLS kept intact.
By default, services are not visible across clusters. Configure the export with a ServiceEntry and export labels:
apiVersion: networking.istio.io/v1
kind: ServiceEntry
metadata:
name: productpage-remote
spec:
hosts:
- productpage.remote-ns.svc.cluster.local
location: MESH_INTERNAL
resolution: DNS
addresses:
- 240.0.0.1
endpoints:
- address: <IP_eastwest_remote>
ports:
tls: 15443This kind of ServiceEntry is installed in all clusters so each one knows how to reach services in a remote cluster through the east-west gateway.
Each cluster has its own CoreDNS, so the svc.cluster.local names are not automatically known across clusters. The solutions:
To use the Istio DNS proxy, enable it on istiod:
spec:
meshConfig:
defaultConfig:
proxyMetadata:
ISTIO_META_DNS_CAPTURE: "true"
ISTIO_META_DNS_AUTO_ALLOCATE: "true"ISTIO_META_DNS_CAPTURE: "true" makes Envoy resolve remote service names locally, reducing dependency on cluster DNS. The 240.0.0.0/8 address range is used for automatic allocation of remote endpoints.
Identity across all clusters comes from the trust domain and a common root CA:
trustDomain and meshID.cluster.local/ns/.../sa/... identity.Set it in MeshConfig:
spec:
meshConfig:
meshID: mesh-produksi
trustDomain: cluster.localmeshID: mesh-produksi identifies the mesh in telemetry and service export. If two meshes want to call each other without fully merging, use mesh-to-mesh federation with mutually recognized trust domains — a rarer and more complex case.
Warning
Uniting two clusters that already have different root CAs requires careful CA rotation. Build the new trust in staging first before touching production.
Episode 16 united many clusters into one mesh: primary-remote, replicated, and external control plane topologies; the east-west gateway with AUTO_PASSTHROUGH mode; cross-cluster service export and DNS; and the consistent trust domain needed for security.
Key takeaways:
In the next episode, episode 17, we will discuss a new, maturing mode: ambient mesh and sidecar-less patterns — the concepts of ztunnel and waypoint proxies, the security and observability differences from the sidecar model, and its stability status in Istio releases.